LCS#1 - Le génie de Jean-Martin Charcot

 


A l'occasion de la semaine du cerveau 2021, je vous propose de plonger dans le Paris du 19ème siècle à la découverte de l'un des plus grands scientifiques de son temps, Jean-Martin Charcot.


A l'hôpital de la Salpêtrière, il fut à l'origine d'une révolution médicale et scientifique. Entouré de brillants médecins, il fit de nombreuses découvertes et décrivit un grand nombre de pathologies, dont la sclérose en plaques et la sclérose latérale amyotrophique. Comment s'y est-il pris ? Que connait-on aujourd'hui de ces pathologies ? Et quel rôle a joué sa femme de ménage dans cette histoire ?



SOURCES :

Bogousslavsky, Julien. "Jean-Martin Charcot and his legacy." Hysteria: The rise of an enigma. Vol. 35. Karger Publishers, 2014. 44-55.

Bogousslavsky, Julien, and Thierry Moulin. "Birth of modern psychiatry and the death of alienism: the legacy of Jean-Martin Charcot." Following Charcot: A Forgotten History of Neurology and Psychiatry. Vol. 29. Karger Publishers, 2011. 1-8.

Zalc, Bernard. "One hundred and fifty years ago Charcot reported multiple sclerosis as a new neurological disease." Brain 141.12 (2018): 3482-3488.

Hardiman, Orla, et al. "Amyotrophic lateral sclerosis." Nature reviews Disease primers 3.1 (2017): 1-19.

White, Michel B. "Jean-Martin Charcot's contributions to the interface between neurology and psychiatry." Canadian journal of neurological sciences 24 (1997): 254-260.

White, Michel B. "Jean-Martin Charcot's contributions to the interface between neurology and psychiatry." Canadian journal of neurological sciences 24 (1997): 254-260.

Katz, Jonathan S., Mazen M. Dimachkie, and Richard J. Barohn. "Amyotrophic lateral sclerosis: A historical perspective." Neurologic clinics 33.4 (2015): 727-734.

-Thompson, Alan J et al., "Multiple sclerosis" The Lancet, Volume 391, Issue 10130, 1622 - 1636


CREDITS PHOTOS - VIDEOS :

- Par Auteur inconnu — http://ihm.nlm.nih.gov/images/B05003, Domaine public, https://commons.wikimedia.org/w/index.php?curid=19004988

- Par https://wellcomeimages.org/indexplus/obf_images/5c/fe/6c5b7e6bc319edd2410d50815c88.jpgGallery: https://wellcomeimages.org/indexplus/image/L0005789.htmlWellcome Collection gallery (2018-04-01): https://wellcomecollection.org/works/jrw9pmsp CC-BY-4.0, CC BY 4.0, https://commons.wikimedia.org/w/index.php?curid=35870817

- Par G._Duchenne.jpgNadar(1820–1910)Autres nomsnom légal : Gaspard-Félix Tournachonpseudonyme : NadarDescriptionphotographe, caricaturiste, écrivain et aéronaute françaisDate de naissance/décès6 avril 182020 mars 1910 / 21 mars 1910Lieu de naissance/décèsParisParisPériode d’activité1854–1910Lieu de travailParisAutorité: Q40116VIAF: 84808952ISNI: 0000 0001 2141 8535ULAN: 500005199SUDOC: 027043827BNF: 119173388WorldCatsecond version uploaded and restored by Jebulonderivative work: PawełMM (talk) — Bibliothèque nationale de France, Domaine public, https://commons.wikimedia.org/w/index.php?curid=9701531

- By User:Dhp1080 - "Anatomy and Physiology" by the US National Cancer Institute's Surveillance, Epidemiology and End Results (SEER) Program ., CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=1474927

- By Neuron_with_oligodendrocyte_and_myelin_sheath.svg: *Complete_neuron_cell_diagram_en.svg: LadyofHatsderivative work: Andrew c (talk) - Neuron_with_oligodendrocyte_and_myelin_sheath.svg, Public Domain, https://commons.wikimedia.org/w/index.php?curid=10888009

- By Roadnottaken, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=3845936

- By Dr. Jana - http://docjana.com/saltatory-conduction/ ; https://www.patreon.com/posts/4374048, CC BY 4.0, https://commons.wikimedia.org/w/index.php?curid=46818964

- By BruceBlaus - Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=44926477

- By Rcchang16 - Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=74940488

- By Philip Van Damme, Wim Robberecht, and Ludo Van Den Bosch - http://dmm.biologists.org/content/10/5/537Philip Van Damme P, Robberecht W, Van Den Bosch L (May 2017). "Modelling amyotrophic lateral sclerosis: progress and possibilities." Disease Models and Mechanisms. 10 (5): 537-549. doi:10.1242/dmm.029058 PMC: 5451175 PMID: 28468939., CC BY 3.0, https://commons.wikimedia.org/w/index.php?curid=75426102

- Par Henry Vandyke Carter — Henry Gray (1918) Anatomy of the Human Body (See "Livre" section below)Bartleby.com: Gray's Anatomy, Planche 664, Domaine public, https://commons.wikimedia.org/w/index.php?curid=541456

- Par User:Polarlys, translation by User:Ericalens — own work (Image:Medulla_spinalis_-_Querschnitt_-_German_and_Latin.svg), translation by User:Ericalens, CC BY 2.5, https://commons.wikimedia.org/w/index.php?curid=2554980

- Image par holdentrils de Pixabay 

- Image par Oberholster Venita de Pixabay 

- Image par Clker-Free-Vector-Images de Pixabay 

- Image par Ashok Tamang de Pixabay